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Microdosing With CBD

Posted by World of Hemp on

If you’re using CBD, you might still be fine-tuning the best way to administer it to get the most out of it. Microdosing is a great way to sustain a balanced endocannabinoid system and is becoming an increasingly popular way to use CBD. If you’re not sure where or how to start, we’ll cover the best method as well as the products that work well with this way of taking your daily dose of CBD. 

What is microdosing? 

Microdosing, as the name implies, is where you take smaller (micro) doses of something. For example, if your daily dose of CBD was 30mg, you might take 15mg in the morning and 15mg in the evening. If you’re microdosing instead, you might instead take 5mg in the morning, 5mg at lunch, 5mg in the afternoon then the remaining 15mg before bed. There’s a number of ways you can break it down and it all really depends on your body chemistry, how much you’re dosing and why you’re using CBD in the first place. 

Why microdose with CBD? 

When people are using CBD, the key is always consistency. The reason for this is that CBD helps maintain the cannabinoid levels in your endocannabinoid system. By supplementing with CBD, you add to your body’s natural levels to help with things like stress and anxiety⁽¹⁾. It can also help with physiological complaints like pain management, inflammation⁽²⁾ and nausea⁽³⁾. 

Some people can experience a mild feeling of drowsiness when they take a higher dose less frequently, while other people can find CBD stimulating to their system. This is less than ideal if you end up feeling tired at work in the morning or a little wired before bed. By taking the same dose but spread throughout the day, those effects will be dulled or completely muted while still delivering the same, or greater, benefits to your body. 

When your cannabinoid levels drop, the ECS doesn’t operate as well as it normally can. Keeping a gradual, sustained flow of CBD is a more subtle and effective way of using it. It’s important to note that different methods of administering CBD have different absorption rates and stay in your body for varying amounts of time. The longest it will stay in your system is with tinctures which are administered sublingually (under the tongue) and remain for around six hours at most. 

While this is quite a long time comparatively speaking, if you take your drops at 7am after breakfast for example, they’ll have left your system by 1pm at the latest. If you’re only taking CBD twice a day and your second dose is at 9pm as you get ready for bed, there’s an 8 hour window where your CBD levels will drop. If you’re using something like vaping you’ll have an even bigger window as the effects of CBD e-liquids have a fast onset, but also wear off after around an hour. 

By taking smaller, measured and more consistent doses, you’ll sustain the amount of CBD in your system. How often you should take it and what kind of dose you’ll need are two things you’ll need to consider, so we’ll break down which products are best for microdosing and how often you’ll need to take them. 

Which products are best for microdosing with? 

The products best for microdosing need to be a few things: quickly absorbed, able to be used in low doses and easy to measure. When you’re taking only a small dose and doing it more frequently, things like tinctures, vaping and edibles are generally the best options to consider first. 

Microdosing with tinctures: 

Tinctures are administered under the tongue, a few drops at a time. Depending on the strength bottle you choose, a single drop might have as low a dose as 2.5mg per drop. This gives you an extreme level of control over how much you take. They’re also very quickly absorbed when applied this way. The mucous membranes under your tongue will absorb around 40% of the CBD you administer and will be taken into the bloodstream in around 20 minutes. It’s also one of the longest lasting ways to take CBD - tinctures will stay in your system between 4 and 6 hours, making them a lower maintenance way to microdose. To sustain your CBD levels with drops we’d suggest taking them three to four times a day - once when you wake up, once late morning, once in the afternoon and a final dose before bed. 

Microdosing with edibles: 

Edibles are another good way of having a slow, measured dose and they’re also a very discreet and easy way to take your CBD. While a little bottle doesn’t take up a lot of space, a packet of mints or gummies is an even more low maintenance option. Generally speaking, they take a little longer to absorb into your system - around 30 minutes to two hours. However, they’ll stay in your system for around 4 hours after that. We’d recommend something that melts in your mouth like CBD infused mints for a quicker absorption rate, but you may also enjoy CBD gummies too. To maintain your CBD levels with edibles generally we’d suggest taking them at 3 hour intervals throughout the day. Most you’ll find will have 5mg to 10mg each, meaning you’ll get approximately 1mg - 2mg per serving so they’re a great option for those of you wanting a lower dose. 

Microdosing with CBD e-liquids: 

Finally, we’d also recommend vaping with CBD e-liquids to microdose. Vaping is a versatile and quick way to maintain your CBD levels because it’s absorbed rapidly through your respiratory system. It’s the fastest to get into your bloodstream, meaning it can reach the cannabinoid receptors in your brain within 30 seconds of you inhaling it. It comes in a range of strengths and if you go for a moderate strength like a 30mg/ml e-liquid, you’ll only need a few puffs at a time to give your body a boost. It’s also absorbed in the highest concentration, with around 70% of what you inhale actually being synthesised by your body. However, it does wear off the most quickly, typically remaining in your system for about an hour. As such, if you’re using vaping we’d suggest taking a few puffs every 30 minutes or so. 

With that being said, you may want to try a combination of products for ease of use and convenience. You might find taking a few drops in the morning and evening while supplementing with vaping or a few CBD mints throughout the day is best. For a more comprehensive look at how each product works, please refer to our guide to choosing the right product for you. 

How do I know which dose to use at each interval? 

The best way to start is by figuring out how much CBD you’d like to take each day. There are a number of factors that go into this including weight, method of administration and the reason you’re taking it. If you’re not sure how much you should be taking, we’d suggest looking through our dosage guide to start with. As a general rule, we’d recommend you start on the lower end of the spectrum and slowly increase until you find just the right amount. 

Once you’ve calculated your dose, you can roughly divide it by the number of doses you’ll need to take each day. Make sure you factor in how long each method stays in your system for so you know how frequently you need to administer each. To find the right microdose, take your total CBD mg for a day and divide it by the number of times you need to take it. 

As a general guide for timeframes we’d suggest: 

  • Tinctures can be taken three to four times a day. Given that your body will have metabolised it at the six hour mark at the latest, every 5 hours is an ideal point to take a few more drops. 
  • Edibles stay in your system for around four hours, so taking them every three hours will sustain your CBD levels. If you’re using something like a mint with a 5mg serving, having one or two at a time 4 times throughout the day is a simple, discreet and easy way to dose. 
  • Due to the fact that vaping wears off most quickly, you’re best off figuring out how much 1ml of e-liquid contains and going from there. For example, a 300mg 10ml bottle will have 30mg per ml. If you’re aiming for 30mg a day, vaping 1ml gradually throughout the day is the most simple way to microdose. A few puffs every 30 minutes or so will sustain your body’s CBD levels. 


  1. Effect of cannabidiol on plasma prolactin, growth hormone and cortisol in human volunteers - ncbi.nlm.nih.gov 
  2. The Endocannabinoid System as an Emerging Target of Pharmacotherapy -  ncbi.nlm.nih.gov
  3. Regulation of nausea and vomiting by cannabinoids - ncbi.nlm.nih.gov 

Medical Disclaimer

The World of Hemp website contains general information about diet, health, wellbeing and nutrition. This is general information and should be considered as is and not as specific medical advice to treat specific conditions. World of Hemp makes no representations or warranties in relation to the health information on this website and as such you should not rely on this information as an alternative to advice given by a doctor or specialist medical practitioner. Read disclaimer in full.

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